Comparative Study Between Ultrasound-Guided Transverse Abdominis Plane Versus Posterior Rectus Sheath Block for Postoperative Analgesia in Midline Laparotomies
DOI:
https://doi.org/10.61919/j74scq69Keywords:
Midline laparotomy, postoperative pain, ultrasound-guided block, posterior rectus sheath block, transversus abdominis plane block, regional anesthesia.Abstract
Background: Postoperative pain following midline laparotomy is severe and contributes to pulmonary impairment, delayed gastrointestinal recovery, and prolonged hospitalization. Although systemic opioids remain the cornerstone of analgesia, their use is limited by adverse effects including respiratory depression, nausea, vomiting, and ileus. Ultrasound-guided fascial plane blocks such as the transversus abdominis plane (TAP) and posterior rectus sheath (PRS) blocks have emerged as effective regional techniques within multimodal analgesia and enhanced recovery after surgery (ERAS) protocols. Objective: To compare the efficacy of ultrasound-guided TAP and PRS blocks for postoperative analgesia in patients undergoing elective midline laparotomy, with primary assessment based on Numeric Rating Scale (NRS) pain scores at 12 hours. Methods: A randomized controlled trial was conducted at Rahman Medical Institute, Peshawar, from 13 April 2025 to 13 July 2025, enrolling 138 patients aged 18–50 years undergoing elective midline laparotomy. Patients were randomized equally to receive either TAP or PRS block under ultrasound guidance in addition to standardized general anesthesia. Postoperative NRS scores were recorded at 2, 6, 12, and 24 hours, and opioid consumption and complications were analyzed. Results: The PRS group reported significantly lower mean NRS scores at all time intervals, with a mean difference of –0.9 (95% CI: –1.24 to –0.56, p < 0.01) at 12 hours. Supplemental opioid use was lower in the PRS group (26.1%) than the TAP group (46.4%), with a relative risk of 0.56 (95% CI: 0.35–0.90). No block-related complications were observed. Conclusion: Ultrasound-guided PRS block provided superior analgesia and opioid-sparing benefits compared to TAP block in midline laparotomy, supporting its integration into ERAS protocols for optimal perioperative pain management.
References
1. Correction: Ultrasound-Guided Transverse Abdominis Plane Block, Ilioinguinal/Iliohypogastric Nerve Block, and Quadratus Lumborum Block for Elective Open Inguinal Hernia Repair in Children: A Randomized Controlled Trial. Reg Anesth Pain Med. 2022;47(6):e2.
2. Alsharari AF, Alshammari FF, Salihu D, Alruwaili MM. Postoperative Pain Management in Children Undergoing Laparoscopic Appendectomy: A Scoping Review. Healthcare (Basel). 2023;11(6).
3. Campoy L, Martin-Flores M, Boesch JM, Moyal MN, Gleed RD, Radhakrishnan S, et al. Transverse Abdominis Plane Injection of Bupivacaine With Dexmedetomidine or a Bupivacaine Liposomal Suspension Yielded Lower Pain Scores and Requirement for Rescue Analgesia in a Randomized Trial in Dogs Undergoing Elective Ovariohysterectomy. Am J Vet Res. 2022;83(9).
4. Di Bella C, Pennasilico L, Staffieri F, Serino F, Palumbo Piccionello A. Ultrasound-Guided Lateral Transversus Abdominis Plane Block in Rabbits: A Cadaveric Study. Animals (Basel). 2021;11(7).
5. Elsakka KM, Das JM, Leslie SW, Allam AE. Ilioinguinal Neuralgia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
6. Espadas-González L, Usón-Casaús JM, Pastor-Sirvent N, Santella M, Ezquerra-Calvo J, Pérez-Merino EM. Evaluation of the Two-Point Ultrasound-Guided Transversus Abdominis Plane Block for Laparoscopic Canine Ovariectomy. Animals (Basel). 2022;12(24).
7. Feng Z, Xue FS, Cheng Y. Letter to the Editor Regarding “Comparison of Ultrasound-Guided Erector Spinae Plane Block and Oblique Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia in Elderly Patients After Laparoscopic Colorectal Surgery: A Prospective Randomized Study.” Pain Ther. 2022;11(4):1507-9.
8. Hirata Y, Gottumukkala V, Ajith J, Schmeisser JA, Ninan EP, Maxwell JE, et al. Laparoscopic Transverse Abdominis Plane Block: How I Do It and a Cost Efficiency Analysis. Langenbecks Arch Surg. 2023;409(1):16.
9. Kamyabnia M, Rastabi HI, Ghadiri A, Jalali MR, Givi ME. Comparison of Incisional, Transverse Abdominis Plane, and Rectus Sheath Blocks in Dogs Undergoing Ovariohysterectomy. Am J Vet Res. 2023;84(8).
10. Li C, Shi J, Jia H. Ultrasound-Guided Transversus Abdominis Plane Block as an Effective Anesthetic Technique for Transverse Colostomy in a High-Risk Elderly Patient: A Case Report. Front Med (Lausanne). 2023;10:1102540.
11. Li SJ, Tong SX, Feng D. Efficacy of Ultrasound-Guided Transverse Abdominal Plane Block for Residual Pain After Pulsed Radiofrequency in Abdominal Acute/Subacute Herpes Zoster-Related Pain. J Ultrasound Med. 2025;44(4):667-79.
12. Liu DX, Zhu ZQ. Ultrasound-Guided Peripheral Trunk Block Technique: A New Approach Gradually Stepping Onto the Stage of Clinical Anesthesia. Ibrain. 2021;7(3):211-26.
13. McCracken S, Lauzadis J, Soffin EM. Ultrasound-Guided Fascial Plane Blocks for Spine Surgery. Curr Opin Anaesthesiol. 2022;35(5):626-33.
14. Mishra N, Bhagat M, Haque E. The Efficacy of Transverse Abdominis Plane Block for Postoperative Analgesia in Laparoscopic Hysterectomy: A Randomized Prospective Study. Cureus. 2023;15(2):e34666.
15. Missett RM, Beig Zali S, Winograd J, Scemama de Gialluly P, Sabouri AS. Intraoperative Ultrasound-Guided Transversus Abdominis Plane Catheters Placed for Postoperative Analgesia Following Pedicled Transverse Rectus Abdominis Myocutaneous Flap Breast Reconstruction: A Case Report. Cureus. 2023;15(5):e39045.
16. Mounika V, Sahu L, Mishra K, Mohapatra PS. A Comparative Evaluation of Postoperative Pain Management Using Erector Spinae Plane Block and Oblique Transverse Abdominis Plane Block in Patients Undergoing Laparoscopic Cholecystectomy. Cureus. 2023;15(3):e35750.
17. Neethirajan SGR, Kurada S, Parameswari A. Efficacy of Dexmedetomidine as an Adjuvant to Bupivacaine in Ultrasound-Guided Transversus Abdominis Plane Block for Laparoscopic Appendicectomy: A Randomised Controlled Study. Turk J Anaesthesiol Reanim. 2020;48(5):364-70.
18. Priyadarshini K, Behera BK, Tripathy BB, Misra S. Ultrasound-Guided Transverse Abdominis Plane Block, Ilioinguinal/Iliohypogastric Nerve Block, and Quadratus Lumborum Block for Elective Open Inguinal Hernia Repair in Children: A Randomized Controlled Trial. Reg Anesth Pain Med. 2022;47(4):217-21.
19. Qi-Hong S, Xu-Yan Z, Xu S, Yan-Jun C, Ke L, Rong W. Comparison of Ultrasound-Guided Erector Spinae Plane Block and Oblique Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia in Elderly Patients After Laparoscopic Colorectal Surgery: A Prospective Randomized Study. Pain Ther. 2021;10(2):1709-18.
20. Xu M, Feng Y, Song X, Fu S, Lu X, Lai J, et al. Combined Ultrasound-Guided Thoracic Paravertebral Nerve Block With Subcostal Transversus Abdominis Plane Block for Analgesia After Total Minimally Invasive Mckeown Esophagectomy: A Randomized, Controlled, and Prospective Study. Pain Ther. 2023;12(2):475-89.
21. Xue Q, Chu Z, Zhu J, Zhang X, Chen H, Liu W, et al. Analgesic Efficacy of Transverse Abdominis Plane Block and Quadratus Lumborum Block in Laparoscopic Sleeve Gastrectomy: A Randomized Double-Blinded Clinical Trial. Pain Ther. 2022;11(2):613-26.
22. Zhang L, Liu Z, Guo J, Jin H, Zhang Z. Effectiveness of Ultrasound-Guided Ilioinguinal and Iliohypogastric Nerve Block in Pediatric Inguinal Hernia Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Med Ultrason. 2024.
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Copyright (c) 2025 Danyal Najam, Mohammad Shafiq, Sardar Saud Abbas, Anum Tariq, Shaharyar Khan, Amber Ali (Author)

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