Analysis of the Sonographic Appearance of Ovarian Endometriosis and Deep Infiltrating Endometriosis

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Amreen Saleem
Hafiz Shahzad Muzammil
Ayesha Ilyas
Amina Imtiaz
Amjad Hussain

Abstract

Background: Endometriosis is a chronic estrogen-dependent gynecological disorder commonly associated with pelvic pain, dysmenorrhea, dyspareunia, and infertility. Transvaginal ultrasonography is increasingly used as a first-line imaging modality for identifying ovarian endometriomas and deep infiltrating endometriosis. Objective: To analyze the sonographic features of ovarian endometriomas and deep infiltrating endometriosis among reproductive-age women undergoing pelvic evaluation at Shalamar Hospital, Lahore. Methods: This cross-sectional observational study included 42 women aged 18–45 years with symptoms suggestive of endometriosis. Participants underwent clinical assessment and transvaginal ultrasonography using a standardized pelvic scanning protocol. Ovarian morphology, lesion laterality, echogenicity, Doppler flow, deep pelvic compartment involvement, and clinical symptoms were recorded. Descriptive statistics were calculated, and reported associations were assessed using appropriate inferential tests. Results: Isolated ovarian endometrioma was identified in 21 participants (50.0%), isolated deep infiltrating endometriosis in 7 (16.7%), combined ovarian endometrioma and deep infiltrating endometriosis in 10 (23.8%), and no lesion in 4 (9.5%). Among 31 participants with ovarian endometrioma, ground-glass echogenicity was observed in 24 (77.4%) and minimal or peripheral Doppler flow in 25 (80.6%). Among 17 participants with deep infiltrating endometriosis, uterosacral ligament involvement was most frequent (70.6%), and all lesions were hypoechoic. Conclusion: Transvaginal ultrasonography provided clinically useful characterization of ovarian endometriomas and deep infiltrating endometriosis, supporting its role as a first-line imaging tool in symptomatic reproductive-age women.

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1.
Amreen Saleem, Hafiz Shahzad Muzammil, Ayesha Ilyas, Amina Imtiaz, Amjad Hussain. Analysis of the Sonographic Appearance of Ovarian Endometriosis and Deep Infiltrating Endometriosis. JHWCR [Internet]. 2026 Jun. 19 [cited 2026 Jun. 19];4(12):1-10. Available from: https://www.jhwcr.com/index.php/jhwcr/article/view/1837

References

1. Czubak P, Herda K, Niewiadomska I, Putowski L, Łańcut M, Masłyk M. Understanding endometriosis: a broad review of its causes, management, and impact. Int J Mol Sci. 2025;26(18):8878.

2. Xu S, Zhang Y, Ye P, Huang Q, Wang Y, Zhang Y, et al. Global, regional, and national burden of endometriosis among women of childbearing age from 1990 to 2021: a cross-sectional analysis from the 2021 Global Burden of Disease Study. Int J Surg. 2025;111(9):5927-40.

3. Alson S, Jokubkiene L, Henic E, Sladkevicius P. Prevalence of endometrioma and deep infiltrating endometriosis at transvaginal ultrasound examination of subfertile women undergoing assisted reproductive treatment. Fertil Steril. 2022;118(5):915-23.

4. Capraș RD, Badea IC, Moldovan M, Gaia-Oltean AI, Badea AF, Telecan T, editors. The diagnostic performance of transvaginal ultrasound for posterior compartment endometriosis compared to laparoscopic and histopathological findings: a systematic review. Healthcare. 2025.

5. Daniilidis A, Grigoriadis G, Dalakoura D, D’Alterio MN, Angioni S, Roman H. Transvaginal ultrasound in the diagnosis and assessment of endometriosis—an overview: how, why, and when. Diagnostics. 2022;12(12):2912.

6. Guerriero S, Ajossa S, Pagliuca M, Borzacchelli A, Deiala F, Springer S, et al. Advances in imaging for assessing pelvic endometriosis. Diagnostics. 2022;12(12):2960.

7. Idle S, Ross J. Meeting of the British Medical Ultrasound Society, 4–6 December 2018, The Point, Emirates Old Trafford, Manchester, UK. Ultrasound. 2019;27(2).

8. Pascoal E, Wessels J, Aas-Eng M, Abrao MS, Condous G, Jurkovic D, et al. Strengths and limitations of diagnostic tools for endometriosis and relevance in diagnostic test accuracy research. Ultrasound Obstet Gynecol. 2022;60(3):309-27.

9. Constantinou CE. Dynamics of female pelvic floor function using urodynamics, ultrasound and magnetic resonance imaging. Eur J Obstet Gynecol Reprod Biol. 2009;144 Suppl 1.

10. Raiza LCP, Bianchi PHM, Piccinato CA, Podgaec S. Sonographic signs of deep infiltrative endometriosis among women submitted to routine transvaginal sonography: clinical and imaging aspects. Einstein (Sao Paulo). 2022;20.

11. Radhika AG, Chawla S, Nanda P, Yadav G, Radhakrishnan G. A multivariate analysis of correlation between severity and duration of symptoms, patient profile and stage of endometriosis. Open J Obstet Gynecol. 2016;6(10):615-22.

12. Raffeld MR. Barriers and facilitators to urogynecologic care: an investigation into patient, provider, and structural factors influencing access and treatment. Philadelphia: Temple University; 2024.

13. Ellis K, Munro D, Clarke J. Endometriosis is undervalued: a call to action. Front Glob Womens Health. 2022;3:902371.

14. Qi Q, Li Y, Chen Z, Luo Z, Zhou T, Zhou J, et al. Update on the pathogenesis of endometriosis-related infertility based on contemporary evidence. Front Endocrinol. 2025;16:1558271.

15. Xu Z, Li Y, Wang Y, Wan Y, Chen J. Transvaginal ultrasound and magnetic resonance imaging in detecting rectosigmoid deep infiltrating endometriosis: a comparative meta-analysis. Front Med. 2025;12:1552185.

16. Ferrero S, Barra F, Perrone U, Paudice M, Vellone VG. Ultrasound diagnosis of bowel endometriosis. Gynecol Obstet Invest. 2025;90(3):268-78.

17. Wu H, Sang X, Zhao S, Chen J, Gu H, Yuan H, et al. Analysis of clinical characteristics, diagnosis, treatment, and postoperative outcomes in deep infiltrating endometriosis: a retrospective study. Eur J Obstet Gynecol Reprod Biol. 2025:114607.

18. Guerriero S, Condous G, Rolla M, Pedrassani M, Leonardi M, Hudelist G, et al. Addendum to consensus opinion from the International Deep Endometriosis Analysis group: sonographic evaluation of superficial endometriosis. Ultrasound Obstet Gynecol. 2025;66(4):541-7.

19. Mick I, Freger SM, Marien M, Gholiof M, Leonardi M. Diagnostic accuracy of transvaginal ultrasonography for endometriosis according to the International Deep Endometriosis Analysis consensus. O&G Open. 2025;2(1).

20. Nagar R, Aharoni S, Leonardi M. Use of intraoperative ultrasound to aid in diagnosis and management of unusual endometrioma. J Endometr Uterine Disord. 2025:100116.

21. Garzon S, Laganà AS, Guerriero S, Alcázar JL, Dababou S, Uccella S, et al. Transvaginal sonography for the preoperative assessment of parametrial deep infiltrating endometriosis: a diagnostic accuracy study. Gynecol Obstet Invest. 2024;89(2):111-9.

22. Mostafavi SRS, Kor E, Sakhaei SM, Kor A. The correlation between ultrasonographic findings and clinical symptoms of pelvic endometriosis. BMC Res Notes. 2024;17(1):108.

23. Bean E, Knez J, Setty T, Tetteh A, Casagrandi D, Naftalin J, et al. Natural history of endometriosis in pregnancy: ultrasound study of morphology of deep endometriosis and ovarian endometrioma. Ultrasound Obstet Gynecol. 2023;62(4):585-93.

24. Chaggar P, Tellum T, Thanatsis N, De Braud L, Setty T, Jurkovic D. Prevalence of deep and ovarian endometriosis in women attending a general gynecology clinic: prospective cohort study. Ultrasound Obstet Gynecol. 2023;61(5):632-41.

25. Ștefan RA, Ștefan PA, Mihu CM, Csutak C, Melincovici CS, Crivii CB, et al. Ultrasonography in the differentiation of endometriomas from hemorrhagic ovarian cysts: the role of texture analysis. J Pers Med. 2021;11(7):611.

26. Alborzi S, Rasekhi A, Shomali Z, Madadi G, Alborzi M, Kazemi M, et al. Diagnostic accuracy of magnetic resonance imaging, transvaginal, and transrectal ultrasonography in deep infiltrating endometriosis. Medicine. 2018;97(8).