Association between Body Mass Index and Operative Difficulty in Laparoscopic Cholecystectomy
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Abstract
Background: Symptomatic gallstone disease and related benign gallbladder disease is a condition that is surgically treated with laparoscopic cholecystectomy. But there are several anatomical, inflammatory and patient-related factors which may make them more or less difficult to operate on. Higher BMI may lead to technical difficulties in laparoscopic surgery including port placement, visibility, retraction, dissection and operative time. Objective: To determine the association between body mass index and operative difficulty in patients undergoing laparoscopic cholecystectomy. Methods: This descriptive cross-sectional study was conducted in the Department of Surgery, Lahore General Hospital, Lahore, Pakistan, from June 2025 to January 2026. The number of patients (N) was 75 those who had undergone laparoscopic cholecystectomy for symptomatic gallstone disease were included through non-probability consecutive sampling technique. The BMI was determined by measured height and weight and patients were classified as normal BMI, overweight, and obese. Intraoperative parameters such as port placement difficulty, dense adhesions, difficulty with dissection of Calot's triangle, blood loss, perforation of gall bladder, spillage of bile, requirement of additional port, conversion to open surgery and operative time were used to assess operative difficulty. SPSS software (version 26) was used to analyze data. The data were statistically analysed by chi-square test and one-way ANOVA where appropriate and the significance level set at <0.05. Results: Among 75 patients, the mean age was 43.6 ± 12.8 years, and the majority were female 49 (65.3%). The mean BMI was 27.8 ± 4.6 kg/m². Normal BMI was observed in 21 (28.0%) patients, overweight in 34 (45.3%), and obesity in 20 (26.7%). Operative difficulty increased with BMI. Difficult surgery was recorded in 2 (9.5%) normal-BMI patients, 7 (20.6%) overweight patients, and 7 (35.0%) obese patients, showing a statistically significant association between BMI and operative difficulty (p = 0.032). Mean operative time also increased significantly across BMI groups, from 42.8 ± 9.6 minutes in normal-BMI patients to 63.7 ± 14.8 minutes in obese patients (p < 0.001). Conclusion: Increased body mass index was significantly associated with greater operative difficulty during laparoscopic cholecystectomy. Obese patients had longer operative time and higher frequencies of difficult port placement, dense adhesions, difficult Calot’s triangle dissection, gallbladder perforation, additional port requirement, and conversion to open surgery. BMI should therefore be considered during preoperative assessment and operative planning.
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1. Nassar AH, Khan KS, Ng HJ, Sallam M. Operative difficulty, morbidity and mortality are unrelated to obesity in elective or emergency laparoscopic cholecystectomy and bile duct exploration. J Gastrointest Surg. 2022;26(9):1863-1872.
2. Fakhoury HM, Yousef Z, Tamim H, Daher S, Attasi AA, Al Ajlan A, et al. Combined effect of age and body mass index on postoperative mortality and morbidity in laparoscopic cholecystectomy patients. 2023;10:1243915.
3. Vannucci M, Laracca GG, Mercantini P, Perretta S, Padoy N, Dallemagne B, et al. Statistical models to preoperatively predict operative difficulty in laparoscopic cholecystectomy: A systematic review. 2022;171(5):1158-1167.
4. Ary Wibowo A, Tri Joko Putra O, Noor Helmi Z, Poerwosusanta H, Kelono Utomo T, Marwan Sikumbang K. A scoring system to predict difficult laparoscopic cholecystectomy: A five-year cross-sectional study. Minim Invasive Surg. 2022;2022(1):3530568.
5. Enami Y, Aoki T, Tomioka K, Hakozaki T, Hirai T, Shibata H, et al. Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis. 2021;11(1):2384.
6. Bansal A, Mahobia HS, Waghoikar G. A clinical study to determine predictive factors for difficult laparoscopic cholecystectomy. Int J Surg. 2020;4(4):126-132.
7. Stanisic V, Milicevic M, Kocev N, Stanisic B. A prospective cohort study for prediction of difficult laparoscopic cholecystectomy. Ann Med Surg. 2020;60:728-733.
8. Rudasill SE, Dillon D, Karunungan K, Mardock AL, Hadaya J, Sanaiha Y, et al. The obesity paradox: underweight patients are at the greatest risk of mortality after cholecystectomy. 2021;170(3):675-681.
9. Di Buono G, Romano G, Galia M, Amato G, Maienza E, Vernuccio F, et al. Difficult laparoscopic cholecystectomy and preoperative predictive factors. 2021;11(1):2559.
10. Wong A, Naidu S, Lancashire RP, Chua TC. The impact of obesity on outcomes in patients undergoing emergency cholecystectomy for acute cholecystitis. ANZ J Surg. 2022;92(5):1091-1096.
11. Karim ST, Chakravarti S, Jain A, Patel G, Dey S. Difficult laparoscopic cholecystectomy predictors and its significance: Our experience. J West Afr Coll Surg. 2022;12(4):56-63.
12. Abdulla MA, Muslim SK, Kalaf AZ. Impact of BMI on laparoscopic cholecystectomy. Basrah J Surg. 2022;22(1):189-193.
13. Russolillo N, Maina C, Langella S, Lo Tesoriere R, Casella M, Ferrero A. Impact of anthropometric data on technical difficulty of laparoscopic liver resections of segments 7 and 8: The CHALLENGE index. Surg Endosc. 2021;35(9):5088-5095.
14. Chen G, Li M, Cao B, Xu Q, Zhang Z. Risk prediction models for difficult cholecystectomy. Visc Med. 2022;17(2):303.
15. Kwan B, Waters PS, Keogh C, Cavallucci DJ, O'Rourke N, Bryant RD. Body mass index and surgical outcomes in laparoscopic liver resections: A systematic review. ANZ J Surg. 2021;91(11):2296-2307.
16. Sucandy I, Attili A, Spence J, Bordeau T, Ross S, Rosemurgy A. The impact of body mass index on perioperative outcomes after robotic liver resection. J Robot Surg. 2020;14(1):41-46.
17. AbdelDayem M, Osgood L, Escofet X, Farag M. A new preoperative scoring system to predict difficulty of laparoscopic cholecystectomy and risk of conversion to open surgery. Int J Surg. 2020;82(4):501-506.
18. Sato M, Endo K, Harada A, Shijo M. Risk factors of postoperative complications in laparoscopic cholecystectomy for acute cholecystitis. J Soc Laparoendosc Surg. 2020;24(4).00049.
19. Chin X, Arachchige SM, Orbell-Smith J, Wysocki AP, Orbell-Smith JL. Preoperative and intraoperative risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy: A systematic review of 30 studies. Cureus. 2023;15(10).
20. Bhandari TR, Khan SA, Jha JL. Prediction of difficult laparoscopic cholecystectomy: An observational study. Ann Med Surg. 2021;72:103060.